Comprehensive Scientific Studies on Lentinula edodes
4+ peer-reviewed studies documenting Shiitake's cholesterol management, immune support, and cardiovascular health benefits.
Landmark human studies demonstrating Shiitake's health benefits in real-world applications.
Citation: Shiitake mushrooms (Lentinula edodes) containing beta-glucans may be beneficial for human health; they have been used in the treatment of cancer, hypertension, and high cholesterol levels. Scientific Reports, 10(1), 7554690.
Research demonstrating Shiitake's benefits for heart health and cholesterol management.
Citation: Eritadenine from shiitake mushroom is a secondary metabolite with hypocholesterolemic, hypotensive and antiparasitic properties, thus promising for pharmaceutical and agricultural applications. Journal of Agricultural and Food Chemistry, 2023.
Research demonstrating Shiitake's immune modulation and support mechanisms.
Citation: Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of Lentinula edodes and Pleurotus ostreatus Edible Mushrooms. International Journal of Molecular Sciences, 22(15), 8348442.
Citation: Immunomodulatory Properties of Polysaccharides from Lentinula edodes. Frontiers in Immunology, 13, 9409024.
Research demonstrating Shiitake's antioxidant capacity and cellular protection.
Citation: Lentinula edodes, a Novel Source of Polysaccharides with Antioxidant Power. Antioxidants, 11(9), 1770.
Moderate - Promising in vitro and animal studies with some clinical evidence
Well-Understood - Beta-glucans and eritadenine for cholesterol and immune support
Excellent - No significant side effects reported in clinical studies
Established - 1-3g/day effective dose range for cardiovascular support
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